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Index > Protein center > SIRT1(Gene name) > Human
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  • SIRT1 (Gene name),
  • NAD-dependent protein deacetylase sirtuin-1 (Protein name ),  SIR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SIRT1(SIR2L1);
    Protein name:
    NAD-dependent protein deacetylase sirtuin-1(hSIRT1);
    Alternative:
    SIR2-like protein 1(hSIR2);Regulatory protein SIR2 homolog 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Found in a complex with PCAF and MYOD1. Interacts with FOXO1; the interaction deacetylates FOXO1, resulting in its nuclear retention and promotion of its transcriptional activity Component of the eNoSC complex, composed of SIRT1, SUV39H1 and RRP8. Interacts with HES1, HEY2 and PML. Interacts with RPS19BP1/AROS. Interacts with CCAR2 (via N-terminus); the interaction disrupts the interaction between SIRT1 and p53/TP53. Interacts with SETD7; the interaction induces the dissociation of SIRT1 from p53/TP53 and increases p53/TP53 activity. Interacts with MYCN, NR1I2, CREBZF, TSC2, TLE1, FOS, JUN, NR0B2, PPARG, NCOR, IRS1, IRS2 and NMNAT1. Interacts with HNF1A; the interaction occurs under nutrient restriction. Interacts with SUZ12; the interaction mediates the association with the PRC4 histone methylation complex which is specific as an association with PCR2 and PCR3 complex variants is not found. Interacts with HIV-1 tat. Interacts with BCL6; leads to a epigenetic repression of specific target genes.
    Function:
    SirtT1 75 kDa fragment: catalytically inactive 75SirT1 may be involved in regulation of apoptosis. May be involved in protecting chondrocytes from apoptotic death by associating with cytochrome C and interfering with apoptosome assembly.
    Subcellular Location:
    SirtT1 75 kDa fragment Cytoplasm Mitochondrion
    Protein Attributes:
    Sequence length:
    747
    Sequence:
    50:
    MADEAALALQ | PGGSPSAAGA | DREAASSPAG | EPLRKRPRRD | GPGLERSPGE | 
    100:
    PGGAAPEREV | PAAARGCPGA | AAAALWREAE | AEAAAAGGEQ | EAQATAAAGE | 
    150:
    GDNGPGLQGP | SREPPLADNL | YDEDDDDEGE | EEEEAAAAAI | GYRDNLLFGD | 
    200:
    EIITNGFHSC | ESDEEDRASH | ASSSDWTPRP | RIGPYTFVQQ | HLMIGTDPRT | 
    250:
    ILKDLLPETI | PPPELDDMTL | WQIVINILSE | PPKRKKRKDI | NTIEDAVKLL | 
    300:
    QECKKIIVLT | GAGVSVSCGI | PDFRSRDGIY | ARLAVDFPDL | PDPQAMFDIE | 
    350:
    YFRKDPRPFF | KFAKEIYPGQ | FQPSLCHKFI | ALSDKEGKLL | RNYTQNIDTL | 
    400:
    EQVAGIQRII | QCHGSFATAS | CLICKYKVDC | EAVRGDIFNQ | VVPRCPRCPA | 
    450:
    DEPLAIMKPE | IVFFGENLPE | QFHRAMKYDK | DEVDLLIVIG | SSLKVRPVAL | 
    500:
    IPSSIPHEVP | QILINREPLP | HLHFDVELLG | DCDVIINELC | HRLGGEYAKL | 
    550:
    CCNPVKLSEI | TEKPPRTQKE | LAYLSELPPT | PLHVSEDSSS | PERTSPPDSS | 
    600:
    VIVTLLDQAA | KSNDDLDVSE | SKGCMEEKPQ | EVQTSRNVES | IAEQMENPDL | 
    650:
    KNVGSSTGEK | NERTSVAGTV | RKCWPNRVAK | EQISRRLDGN | QYLFLPPNRY | 
    700:
    IFHGAEVYSD | SEDDVLSSSS | CGSNSDSGTC | QSPSLEEPME | DESEIEEFYN | 
    747:
    GLEDEPDVPE | RAGGAGFGTD | GDDQEAINEA | ISVKQEVTDM | NYPSNKS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    UniGene:
    SMR:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human hSIRT1
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    E3949h
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    ELISA Kit for Human hSIRT1
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    ELISA Kit for Human hSIRT1
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    ELISA Kit for Human hSIRT1
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    E3949m
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    Packing:
    96T
    CLIA Kit for Human hSIRT1
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    U3949h
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    Packing:
    96T
    CLIA Kit for Human hSIRT1
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    U3949h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human hSIRT1
    Cat.:
    U3949m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human hSIRT1
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    U3949m
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    Polyclonal Antibody for Human hSIRT1
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    P3949Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human hSIRT1
    Cat.:
    P3949Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human hSIRT1
    Cat.:
    P3949Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human hSIRT1
    Cat.:
    P3949Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human hSIRT1
    Monoclonal Antibody for Human hSIRT1
    Monoclonal Antibody for Human hSIRT1
    Monoclonal Antibody for Human hSIRT1
    Protein for Human hSIRT1
    Protein for Human hSIRT1
    Protein for Human hSIRT1
    Protein for Human hSIRT1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity."
      Frye R.A.
      Biochem. Biophys. Res. Commun.260:273-279(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Testis.
    2. 2.
      "Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression."
      Takata T. , Ishikawa F.
      Biochem. Biophys. Res. Commun.301:250-257(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH HES1 AND HEY2;MUTAGENESIS OF HIS-363
    3. 3.
      NIEHS SNPs program
      Submitted (2005-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLU-3
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 124-747
      tissue: Prostate.
    6. 6.
      "hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase."
      Vaziri H. , Dessain S.K. , Ng Eaton E. , Imai S. , Frye R.A. , Pandita T.K. , Guarente L. , Weinberg R.A.
      Cell107:149-159(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF TP53;SUBCELLULAR LOCATION;MUTAGENESIS OF HIS-363
    7. 7.
      "Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence."
      Langley E. , Pearson M. , Faretta M. , Bauer U.-M. , Frye R.A. , Minucci S. , Pelicci P.G. , Kouzarides T.
      EMBO J.21:2383-2396(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME ACTIVITY;SUBCELLULAR LOCATION;INTERACTION WITH PML;MUTAGENESIS OF HIS-363
    8. 8.
      "Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1."
      Bitterman K.J. , Anderson R.M. , Cohen H.Y. , Latorre-Esteves M. , Sinclair D.A.
      J. Biol. Chem.277:45099-45107(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
    9. 9.
      "Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan."
      Howitz K.T. , Bitterman K.J. , Cohen H.Y. , Lamming D.W. , Lavu S. , Wood J.G. , Zipkin R.E. , Chung P. , Kisielewski A. , Zhang L.-L. , Scherer B. , Sinclair D.A.
      Nature425:191-196(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
    10. 10.
      "Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase."
      Frye R.A. , Mayo M.W.
      EMBO J.23:2369-2380(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    11. 11.
      "Mammalian SIRT1 represses forkhead transcription factors."
      Motta M.C. , Divecha N. , Lemieux M. , Kamel C. , Chen D. , Gu W. , Bultsma Y. , McBurney M. , Guarente L.
      Cell116:551-563(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF FOXO3;FUNCTION IN REGULATION OF FOXO3
    12. 12.
      "FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)."
      van der Horst A. , Tertoolen L.G.J. , de Vries-Smits L.M.M. , Frye R.A. , Medema R.H. , Burgering B.M.T.
      J. Biol. Chem.279:28873-28879(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF MLLT7
    13. 13.
      "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin."
      Vaquero A. , Scher M. , Lee D. , Erdjument-Bromage H. , Tempst P. , Reinberg D.
      Mol. Cell16:93-105(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF FOXO3;FUNCTION IN REGULATION OF FOXO3
    15. 15.
      "Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase."
      Cohen H.Y. , Miller C. , Bitterman K.J. , Wall N.R. , Hekking B. , Kessler B. , Howitz K.T. , Gorospe M. , de Cabo R. , Sinclair D.A.
      Science305:390-392(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF XRCC6;INDUCTION BY CR
    16. 16.
      "Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation."
      Yang Y. , Hou H. , Haller E.M. , Nicosia S.V. , Bai W.
      EMBO J.24:1021-1032(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FHL2;FUNCTION IN DEACETYLATION OF FOXO1;FUNCTION IN REGULATION OF FOXO1
    17. 17.
      "Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins."
      Michishita E. , Park J.Y. , Burneskis J.M. , Barrett J.C. , Horikawa I.
      Mol. Biol. Cell16:4623-4635(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    18. 18.
      "Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications."
      Zhao X. , Sternsdorf T. , Bolger T.A. , Evans R.M. , Yao T.-P.
      Mol. Cell. Biol.25:8456-8464(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF MEF2D;INTERACTION WITH HDAC4
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT
    20. 20.
      "Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation."
      Kuzmichev A. , Margueron R. , Vaquero A. , Preissner T.S. , Scher M. , Kirmizis A. , Ouyang X. , Brockdorff N. , Abate-Shen C. , Farnham P.J. , Reinberg D.
      Proc. Natl. Acad. Sci. U.S.A.102:1859-1864(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH THE PRC4 COMPLEX;INTERACTION WITH SUZ12
    21. 21.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    22. 22.
      "Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage."
      Wang C. , Chen L. , Hou X. , Li Z. , Kabra N. , Ma Y. , Nemoto S. , Finkel T. , Gu W. , Cress W.D. , Chen J.
      Nat. Cell Biol.8:1025-1031(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH E2F1
    23. 23.
      "Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1."
      Wong S. , Weber J.D.
      Biochem. J.407:451-460(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF RB1
    24. 24.
      "Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription."
      Ghosh H.S. , Spencer J.V. , Ng B. , McBurney M.W. , Robbins P.D.
      Biochem. J.408:105-111(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TLE1
    25. 25.
      "SIRT1 promotes DNA repair activity and deacetylation of Ku70."
      Jeong J. , Juhn K. , Lee H. , Kim S.H. , Min B.H. , Lee K.M. , Cho M.H. , Park G.H. , Lee K.H.
      Exp. Mol. Med.39:8-13(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF XRCC6;FUNCTION IN DNA REPAIR
    26. 26.
      "SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity."
      Dai J.M. , Wang Z.Y. , Sun D.C. , Lin R.X. , Wang S.Q.
      J. Cell. Physiol.210:161-166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF TP73;FUNCTION IN REGULATION OF TP73
    27. 27.
      "Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor."
      Dai Y. , Ngo D. , Forman L.W. , Qin D.C. , Jacob J. , Faller D.V.
      Mol. Endocrinol.21:1807-1821(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN AR-DEPENDENT REPRESSION
    28. 28.
      "Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity."
      Kim E.-J. , Kho J.-H. , Kang M.-R. , Um S.-J.
      Mol. Cell28:277-290(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RPS19BP1
    29. 29.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    30. 30.
      "SIRT1 deacetylates and positively regulates the nuclear receptor LXR."
      Li X. , Zhang S. , Blander G. , Tse J.G. , Krieger M. , Guarente L.
      Mol. Cell28:91-106(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF NR1H3 AND NR1H2
    31. 31.
      "SIRT1 regulates the function of the Nijmegen breakage syndrome protein."
      Yuan Z. , Zhang X. , Sengupta N. , Lane W.S. , Seto E.
      Mol. Cell27:149-162(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF NBN;FUNCTION IN DNA REPAIR
    32. 32.
      "An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity."
      Stankovic-Valentin N. , Deltour S. , Seeler J. , Pinte S. , Vergoten G. , Guerardel C. , Dejean A. , Leprince D.
      Mol. Cell. Biol.27:2661-2675(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF HIC1
    33. 33.
      "SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation."
      Vaquero A. , Scher M. , Erdjument-Bromage H. , Tempst P. , Serrano L. , Reinberg D.
      Nature450:440-444(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF HIS-363
    34. 34.
      "SIRT1 regulates circadian clock gene expression through PER2 deacetylation."
      Asher G. , Gatfield D. , Stratmann M. , Reinke H. , Dibner C. , Kreppel F. , Mostoslavsky R. , Alt F.W. , Schibler U.
      Cell134:317-328(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    35. 35.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE ENOSC COMPLEX;FUNCTION;MUTAGENESIS OF HIS-363
    36. 36.
      "JNK2-dependent regulation of SIRT1 protein stability."
      Ford J. , Ahmed S. , Allison S. , Jiang M. , Milner J.
      Cell Cycle7:3091-3097(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-27 AND SER-47
    37. 37.
      "Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation."
      Kwon H.S. , Brent M.M. , Getachew R. , Jayakumar P. , Chen L.F. , Schnolzer M. , McBurney M.W. , Marmorstein R. , Greene W.C. , Ott M.
      Cell Host Microbe3:158-167(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT;FUNCTION IN T-CELL ACTIVATION
    38. 38.
      "Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation."
      Li K. , Casta A. , Wang R. , Lozada E. , Fan W. , Kane S. , Ge Q. , Gu W. , Orren D. , Luo J.
      J. Biol. Chem.283:7590-7598(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF WRN;FUNCTION IN DNA DAMAGE
    39. 39.
      "SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation."
      Lan F. , Cacicedo J.M. , Ruderman N. , Ido Y.
      J. Biol. Chem.283:27628-27635(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF STK11
    40. 40.
      "DBC1 is a negative regulator of SIRT1."
      Kim J.-E. , Chen J. , Lou Z.
      Nature451:583-586(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CCAR2;ENZYME REGULATION;MUTAGENESIS OF HIS-363;IDENTIFICATION BY MASS SPECTROMETRY
    41. 41.
      "Negative regulation of the deacetylase SIRT1 by DBC1."
      Zhao W. , Kruse J.-P. , Tang Y. , Jung S.Y. , Qin J. , Gu W.
      Nature451:587-590(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CCAR2;ENZYME REGULATION
    42. 42.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-14; SER-26; SER-27; SER-47; SER-159; SER-162; SER-172; SER-173; THR-530; THR-544; SER-545; THR-719 AND SER-747;MUTAGENESIS OF THR-530 AND SER-540
    43. 43.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-719;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    44. 44.
      "A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy."
      Lee I.H. , Cao L. , Mostoslavsky R. , Lombard D.B. , Liu J. , Bruns N.E. , Tsokos M. , Alt F.W. , Finkel T.
      Proc. Natl. Acad. Sci. U.S.A.105:3374-3379(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF ATG5; ATG7 AND MAP1LC3B;FUNCTION IN AUTOPHAGY
    45. 45.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    46. 46.
      "Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2."
      Zschoernig B. , Mahlknecht U.
      Biochem. Biophys. Res. Commun.381:372-377(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-659 AND SER-661;MUTAGENESIS OF SER-659; SER-661 AND SER-684
    47. 47.
      "Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD."
      Du J. , Jiang H. , Lin H.
      Biochemistry48:2878-2890(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    48. 48.
      "Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation."
      Purushotham A. , Schug T.T. , Xu Q. , Surapureddi S. , Guo X. , Li X.
      Cell Metab.9:327-338(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPARA
    49. 49.
      "Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation."
      Xie Y.B. , Park J.H. , Kim D.K. , Hwang J.H. , Oh S. , Park S.B. , Shong M. , Lee I.K. , Choi H.S.
      J. Biol. Chem.284:28762-28774(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CREBZF
    50. 50.
      "A c-Myc-SIRT1 feedback loop regulates cell growth and transformation."
      Yuan J. , Minter-Dykhouse K. , Lou Z.
      J. Cell Biol.185:203-211(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF MYC;FUNCTION IN REGULATION OF MYC
    51. 51.
      "hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage."
      Pediconi N. , Guerrieri F. , Vossio S. , Bruno T. , Belloni L. , Schinzari V. , Scisciani C. , Fanciulli M. , Levrero M.
      Mol. Cell. Biol.29:1989-1998(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF PCAF;FUNCTION IN DNA REPAIR
    52. 52.
      "JNK1 phosphorylates SIRT1 and promotes its enzymatic activity."
      Nasrin N. , Kaushik V.K. , Fortier E. , Wall D. , Pearson K.J. , de Cabo R. , Bordone L.
      PLoS ONE4:E8414-E8414(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-27; SER-47 AND THR-530;MUTAGENESIS OF SER-27; SER-47 AND THR-530;SUBCELLULAR LOCATION
    53. 53.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-530; SER-535 AND THR-719;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    54. 54.
      "SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells."
      Zu Y. , Liu L. , Lee M.Y. , Xu C. , Liang Y. , Man R.Y. , Vanhoutte P.M. , Wang Y.
      Circ. Res.106:1384-1393(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF STK11
    55. 55.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR HOMOLOGOUS RECOMBINATION
    56. 56.
      "SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages."
      Zhang R. , Chen H.Z. , Liu J.J. , Jia Y.Y. , Zhang Z.Q. , Yang R.F. , Zhang Y. , Xu J. , Wei Y.S. , Liu D.P. , Liang C.C.
      J. Biol. Chem.285:7097-7110(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOS AND JUN
    57. 57.
      "SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60."
      Wang J. , Chen J.
      J. Biol. Chem.285:11458-11464(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF KAT5
    58. 58.
      "SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism."
      Ponugoti B. , Kim D.H. , Xiao Z. , Smith Z. , Miao J. , Zang M. , Wu S.Y. , Chiang C.M. , Veenstra T.D. , Kemper J.K.
      J. Biol. Chem.285:33959-33970(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF SREBF1
    59. 59.
      "Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha."
      Lim J.H. , Lee Y.M. , Chun Y.S. , Chen J. , Kim J.E. , Park J.W.
      Mol. Cell38:864-878(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF HIF1A;FUNCTION IN REGULATION OF HIF1A
    60. 60.
      "SIRT1 regulates UV-induced DNA repair through deacetylating XPA."
      Fan W. , Luo J.
      Mol. Cell39:247-258(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF XPA
    61. 61.
      "SIRT1 deacetylates APE1 and regulates cellular base excision repair."
      Yamamori T. , DeRicco J. , Naqvi A. , Hoffman T.A. , Mattagajasingh I. , Kasuno K. , Jung S.B. , Kim C.S. , Irani K.
      Nucleic Acids Res.38:832-845(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF APEX1;FUNCTION IN DNA REPAIR;MUTAGENESIS OF HIS-363;INDUCTION;SUBCELLULAR LOCATION
    62. 62.
      "Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation."
      Chanda D. , Xie Y.B. , Choi H.S.
      Nucleic Acids Res.38:4607-4619(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NR0B2
    63. 63.
      "SIRT1 negatively regulates the mammalian target of rapamycin."
      Ghosh H.S. , McBurney M. , Robbins P.D.
      PLoS ONE5:E9199-E9199(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TSC2
    64. 64.
      "SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53."
      Lynch C.J. , Shah Z.H. , Allison S.J. , Ahmed S.U. , Ford J. , Warnock L.J. , Li H. , Serrano M. , Milner J.
      PLoS ONE5:E13502-E13502(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 2);FUNCTION (ISOFORM 2);INDUCTION (ISOFORM 2);INTERACTION WITH TP53 AND RPS19BP1
    65. 65.
      "Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C."
      Ming M. , Shea C.R. , Guo X. , Li X. , Soltani K. , Han W. , He Y.Y.
      Proc. Natl. Acad. Sci. U.S.A.107:22623-22628(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR;SUPPRESSION OF XPC
    66. 66.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14 AND SER-47;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    67. 67.
      "SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2."
      Hirschey M.D. , Shimazu T. , Capra J.A. , Pollard K.S. , Verdin E.
      Aging (Albany NY)3:635-642(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF HMGCS1
    68. 68.
      "Tumor necrosis factor alpha-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes."
      Dvir-Ginzberg M. , Gagarina V. , Lee E.J. , Booth R. , Gabay O. , Hall D.J.
      Arthritis Rheum.63:2363-2373(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROCESSING
    69. 69.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    70. 70.
      "EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1."
      Pradhan A.K. , Kuila N. , Singh S. , Chakraborty S.
      Biochim. Biophys. Acta1809:269-275(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF MECOM
    71. 71.
      "Energy sensing factors PGC-1alpha and SIRT1 modulate PXR expression and function."
      Buler M. , Aatsinki S.M. , Skoumal R. , Hakkola J.
      Biochem. Pharmacol.82:2008-2015(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR1I2
    72. 72.
      "Sirt1 deacetylates c-Myc and promotes c-Myc/Max association."
      Mao B. , Zhao G. , Lv X. , Chen H.Z. , Xue Z. , Yang B. , Liu D.P. , Liang C.C.
      Int. J. Biochem. Cell Biol.43:1573-1581(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF MYC;FUNCTION IN REGULATION OF MYC
    73. 73.
      "MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation."
      Yuan F. , Xie Q. , Wu J. , Bai Y. , Mao B. , Dong Y. , Bi W. , Ji G. , Tao W. , Wang Y. , Yuan Z.
      J. Biol. Chem.286:6940-6945(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY STK4/MST1
    74. 74.
      "Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1."
      Back J.H. , Rezvani H.R. , Zhu Y. , Guyonnet-Duperat V. , Athar M. , Ratner D. , Kim A.L.
      J. Biol. Chem.286:19100-19108(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN APOPTOSIS;PHOSPHORYLATION AT SER-47;MUTAGENESIS OF SER-47 AND PHE-474
    75. 75.
      "Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection."
      Bosch-Presegue L. , Raurell-Vila H. , Marazuela-Duque A. , Kane-Goldsmith N. , Valle A. , Oliver J. , Serrano L. , Vaquero A.
      Mol. Cell42:210-223(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN STABILIZATION OF SUV39H1
    76. 76.
      "SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities."
      Peng L. , Yuan Z. , Ling H. , Fukasawa K. , Robertson K. , Olashaw N. , Koomen J. , Chen J. , Lane W.S. , Seto E.
      Mol. Cell. Biol.31:4720-4734(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF DNMT1;FUNCTION IN REGULATION OF DNMT1
    77. 77.
      "SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability."
      Marshall G.M. , Liu P.Y. , Gherardi S. , Scarlett C.J. , Bedalov A. , Xu N. , Iraci N. , Valli E. , Ling D. , Thomas W. , van Bekkum M. , Sekyere E. , Jankowski K. , Trahair T. , Mackenzie K.L. , Haber M. , Norris M.D. , Biankin A.V. , more...
      PLoS Genet.7:E1002135-E1002135(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF MYCN;INTERACTION WITH MYCN
    78. 78.
      "The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO."
      Rizki G. , Iwata T.N. , Li J. , Riedel C.G. , Picard C.L. , Jan M. , Murphy C.T. , Lee S.S.
      PLoS Genet.7:E1002235-E1002235(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HCFC1
    79. 79.
      "Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)."
      Liu X. , Wang D. , Zhao Y. , Tu B. , Zheng Z. , Wang L. , Wang H. , Gu W. , Roeder R.G. , Zhu W.G.
      Proc. Natl. Acad. Sci. U.S.A.108:1925-1930(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SETD7;MUTAGENESIS OF LYS-233; LYS-235; LYS-236 AND LYS-238
    80. 80.
      "The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy."
      Sundaresan N.R. , Pillai V.B. , Wolfgeher D. , Samant S. , Vasudevan P. , Parekh V. , Raghuraman H. , Cunningham J.M. , Gupta M. , Gupta M.P.
      Sci. Signal.4:RA46-RA46(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF AKT1;FUNCTION IN REGULATION OF AKT1
    81. 81.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-14; SER-47 AND THR-719;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    82. 82.
      "75kDa SirT1 blocks TNFalpha-mediated apoptosis in human osteoarthritic chondrocytes."
      Oppenheimer H. , Gabay O. , Meir H. , Haze A. , Kandel L. , Liebergall M. , Gagarina V. , Lee E.J. , Dvir-Ginzberg M.
      Arthritis Rheum.64:718-728(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION (SIRTT1 75 KDA FRAGMENT);SUBCELLULAR LOCATION (75SIRT1)
    83. 83.
      "SIRT1 links CIITA deacetylation to MHC II activation."
      Wu X. , Kong X. , Chen D. , Li H. , Zhao Y. , Xia M. , Fang M. , Li P. , Fang F. , Sun L. , Tian W. , Xu H. , Yang Y. , Qi X. , Gao Y. , Sha J. , Chen Q. , Xu Y.
      Nucleic Acids Res.39:9549-9558(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF CIITA
    84. 84.
      "PML regulates PER2 nuclear localization and circadian function."
      Miki T. , Xu Z. , Chen-Goodspeed M. , Liu M. , Van Oort-Jansen A. , Rea M.A. , Zhao Z. , Lee C.C. , Chang K.S.
      EMBO J.31:1427-1439(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF PML
    85. 85.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    86. 86.
      "Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation."
      Wang F. , Chan C.H. , Chen K. , Guan X. , Lin H.K. , Tong Q.
      Oncogene31:1546-1557(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF FOXO3;FUNCTION IN REGULATION OF FOXO3
    87. 87.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    88. 88.
      "Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage."
      Kim W. , Kim J.E.
      Cancer Lett.333:180-186(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CCAR2
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